Anemia

The most serious danger is to brain development, which can result in irreversible damage. Higher levels can harm both children and adults' kidneys and nervous systems. Seizures, unconsciousness, and death have all been linked to high levels of lead.

What effect does lead have on anemia?

Chronic lead poisoning impairs hemoglobin production by interfering with enzymatic stages in the heme synthesis pathway, resulting in a reduction in red blood cells and an increased risk of anemia. Lead absorption can cause iron deficiency, which can lead to anemia.

What are some of the health consequences of lead exposure?

High levels of lead exposure can cause anemia, paralysis, kidney and brain damage. Lead poisoning can be fatal in excessive doses. Because lead can pass through the placental barrier, pregnant women who are exposed to it risk exposing their unborn child. The neural system of a developing newborn can be harmed by lead.

What effect does lead have on blood cells?

The majority of lead-related kidney consequences or disorders are caused by continuous chronic exposure, current high acute exposure, or latent effects of previous chronic lead exposure. Lead inhibits many enzymes involved in heme production, resulting in a drop in blood hemoglobin levels.

What sort of anemia is linked to lead poisoning?

Hypochromic microcytic anemia and basophilic stippling of red blood cells are symptoms of lead poisoning. Iron deficiency anemia, which frequently coexists with lead toxicity, is characterized by hypochromia and microcytosis.

What is the time it takes for lead to leave the body?

Lead enters the body through the bloodstream and travels to soft tissues such the liver, kidneys, lungs, brain, spleen, muscles, and heart. Lead has a half-life of roughly one month in blood, 1-1.5 months in soft tissue, and 25-30 years in bone (ATSDR 2007).